Cyril Mamotte joined Curtin University in 2005 following 22 years of clinical experience at Royal Perth Hospital, with the experience and engagement with the profession informing his teaching and research. He is a Clinical Biochemist, Molecular Geneticist, and holds professional qualifications in Clinical Biochemistry (MAACB) and Molecular Genetics (MHGSA). He is also a Fellow of Faculty of Science of the RCPA (FFsc(RCPA)), and has international and national recognition for his research and discipline expertise.

He has a sustained record of significant leadership roles including as School Director of Graduate Research (2010-2013, 2018-current), Deputy Head of School (2014- end of 2017), and as its Chair, currently leads the Health Sciences Faculty Graduate Research Committee.

His research and publication record covers both basic and translational research, from studies on lipid metabolism, and their genetic and therapeutic modulators, to influences on diverse pathophysiological processes and complex diseases (atherosclerosis, immune responses, and diabetes). He also conducts translational studies more directly relevant to the practice of medicine including the development and application of diagnostics tests.

His teaching experience is broad including roles as Chair of the Board of Examiners and Program coordination to Unit coordination, development, and the delivery of lectures and demonstrations. His career spans the teaching of undergraduates to teaching of professional scientists in the context of continual professional development. In context of community and industry engagement, he is a well known member of the Medical Science community, serving on numerous national and international committees pertaining to the practice of laboratory medicine.